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Gene: Ift140 (intraflagellar transport 140) Mus musculus
Symbol: Ift140
Name: intraflagellar transport 140
Description: Involved in several processes, including cilium organization; embryonic organ development; and nervous system development. Localizes to cytoskeleton; intraciliary transport particle A; and photoreceptor cell cilium. Is expressed in diaphragm; lung; metanephros; and retina. Used to study asphyxiating thoracic dystrophy 1 and short-rib thoracic dysplasia 9 with or without polydactyly. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Orthologous to human IFT140 (intraflagellar transport 140); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; cadmium sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI661311; intraflagellar transport 140 homolog; intraflagellar transport protein 140 homolog; MGC170632; mKIAA0590; T-complex expressed gene 5; Tce5; WD and tetratricopeptide repeats 2; WD and tetratricopeptide repeats protein 2; Wdtc2
Homo sapiens (human) : IFT140 (intraflagellar transport 140)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ift140 (intraflagellar transport 140)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ift140 (intraflagellar transport 140)
Pan paniscus (bonobo/pygmy chimpanzee) : IFT140 (intraflagellar transport 140)
Canis lupus familiaris (dog) : IFT140 (intraflagellar transport 140)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ift140 (intraflagellar transport 140)
Sus scrofa (pig) : IFT140 (intraflagellar transport 140)
Chlorocebus sabaeus (African green monkey) : IFT140 (intraflagellar transport 140)
Heterocephalus glaber (naked mole-rat) : Ift140 (intraflagellar transport 140)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1725,016,085 - 25,099,495 (+)EnsemblGRCm38mm10GRCm38
GRCm381725,016,083 - 25,099,499 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371725,153,031 - 25,236,444 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,744,323 - 24,827,086 (+)NCBImm8
Celera1725,543,013 - 25,624,378 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ift140
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553664
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.