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Gene: Cdk5r1 (cyclin-dependent kinase 5, regulatory subunit 1 (p35)) Mus musculus
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Symbol: Cdk5r1
Name: cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CRRD ID: 1553698
Description: Exhibits several functions, including Hsp90 protein binding activity; cyclin-dependent protein serine/threonine kinase activator activity; and enzyme binding activity. Involved in several processes, including nervous system development; neuron cell-cell adhesion; and regulation of cytoskeleton organization. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1); PARTICIPATES IN Reelin signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDK5 activator 1; Cdk5r; cyclin-dependent kinase 5 activator 1; cyclin-dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5, regulatory subunit (p35) 1; D11Bwg0379e; p2; p25; p3; p35; TPKII regulatory subunit
Orthologs:
Homo sapiens (human) : CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk5r1 (cyclin-dependent kinase 5 regulatory subunit 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk5r1 (cyclin dependent kinase 5 regulatory subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)
Canis lupus familiaris (dog) : CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk5r1 (cyclin dependent kinase 5 regulatory subunit 1)
Sus scrofa (pig) : CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)
Chlorocebus sabaeus (African green monkey) : CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)
Heterocephalus glaber (naked mole-rat) : Cdk5r1 (cyclin dependent kinase 5 regulatory subunit 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1180,477,023 - 80,481,184 (+)EnsemblGRCm38mm10GRCm38
GRCm381180,477,023 - 80,481,184 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371180,290,548 - 80,294,681 (+)NCBIGRCm37mm9NCBIm37
MGSCv361180,293,241 - 80,297,376 (+)NCBImm8
Celera1190,115,053 - 90,119,186 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1147.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cdk5r1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553698
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.