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Gene: Id3 (inhibitor of DNA binding 3) Mus musculus
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Symbol: Id3
Name: inhibitor of DNA binding 3
Description: Exhibits several functions, including DNA-binding transcription factor activity; leptomycin B binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; cellular response to leptomycin B; and negative regulation of cell differentiation. Localizes to the cytoplasm and nucleus. Used to study Sjogren's syndrome. Is expressed in several structures, including alimentary system; central nervous system; limb; metanephros; and sensory organ. Orthologous to human ID3 (inhibitor of DNA binding 3, HLH protein); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHb25; DNA-binding protein inhibitor ID-3; Hlh462; ID-like protein inhibitor HLH 462; Idb3; inhibitor of differentiation 3
Orthologs:
Homo sapiens (human) : ID3 (inhibitor of DNA binding 3, HLH protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Id3 (inhibitor of DNA binding 3, HLH protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Id3 (inhibitor of DNA binding 3, HLH protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ID3 (inhibitor of DNA binding 3, HLH protein)
Canis lupus familiaris (dog) : ID3 (inhibitor of DNA binding 3, HLH protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Id3 (inhibitor of DNA binding 3, HLH protein)
Sus scrofa (pig) : ID3 (inhibitor of DNA binding 3, HLH protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384136,143,822 - 136,145,392 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374135,699,737 - 135,701,307 (+)NCBIGRCm37mm9NCBIm37
MGSCv364135,415,898 - 135,417,463 (+)NCBImm8
Celera4134,340,192 - 134,341,762 (+)NCBICelera
Cytogenetic Map4 D3NCBI
cM Map468.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Id3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553777
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.