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Gene: Id3 (inhibitor of DNA binding 3) Mus musculus
Symbol: Id3
Name: inhibitor of DNA binding 3
Description: Exhibits several functions, including DNA-binding transcription factor activity; leptomycin B binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; cellular response to leptomycin B; and negative regulation of cell differentiation. Localizes to the cytoplasm and nucleus. Used to study Sjogren's syndrome. Is expressed in several structures, including alimentary system; central nervous system; limb; metanephros; and sensory organ. Orthologous to human ID3 (inhibitor of DNA binding 3, HLH protein); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHb25; DNA-binding protein inhibitor ID-3; Hlh462; ID-like protein inhibitor HLH 462; Idb3; inhibitor of differentiation 3
Homo sapiens (human) : ID3 (inhibitor of DNA binding 3, HLH protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Id3 (inhibitor of DNA binding 3, HLH protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Id3 (inhibitor of DNA binding 3, HLH protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ID3 (inhibitor of DNA binding 3, HLH protein)
Canis lupus familiaris (dog) : ID3 (inhibitor of DNA binding 3, HLH protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Id3 (inhibitor of DNA binding 3, HLH protein)
Sus scrofa (pig) : ID3 (inhibitor of DNA binding 3, HLH protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384136,143,822 - 136,145,392 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374135,699,737 - 135,701,307 (+)NCBIGRCm37mm9NCBIm37
MGSCv364135,415,898 - 135,417,463 (+)NCBImm8
Celera4134,340,192 - 134,341,762 (+)NCBICelera
Cytogenetic Map4 D3NCBI
cM Map468.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Id3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553777
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.