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Gene: Ibtk (inhibitor of Bruton agammaglobulinemia tyrosine kinase) Mus musculus
Symbol: Ibtk
Name: inhibitor of Bruton agammaglobulinemia tyrosine kinase
Description: Predicted to have protein kinase binding activity and protein tyrosine kinase inhibitor activity. Predicted to be involved in negative regulation of protein phosphorylation and release of sequestered calcium ion into cytosol. Predicted to localize to the cell; cytoplasm; and nucleoplasm. Is expressed in early conceptus and genitourinary system. Orthologous to human IBTK (inhibitor of Bruton tyrosine kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5430411K16Rik; AA409502; BTKI; inhibitor of Bruton tyrosine kinase; mKIAA1417
Homo sapiens (human) : IBTK (inhibitor of Bruton tyrosine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ibtk (inhibitor of Bruton tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ibtk (inhibitor of Bruton tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : IBTK (inhibitor of Bruton tyrosine kinase)
Canis lupus familiaris (dog) : IBTK (inhibitor of Bruton tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ibtk (inhibitor of Bruton tyrosine kinase)
Sus scrofa (pig) : IBTK (inhibitor of Bruton tyrosine kinase)
Chlorocebus sabaeus (green monkey) : IBTK (inhibitor of Bruton tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Ibtk (inhibitor of Bruton tyrosine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl985,687,360 - 85,749,334 (-)Ensembl
GRCm38985,687,359 - 85,750,703 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37985,580,963 - 85,637,766 (-)NCBIGRCm37mm9NCBIm37
MGSCv36985,484,074 - 85,547,147 (-)NCBImm8
Celera982,775,463 - 82,837,627 (-)NCBICelera
Cytogenetic Map9 E3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ibtk
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1553811
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.