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Gene: Rasgrp2 (RAS, guanyl releasing protein 2) Mus musculus
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Symbol: Rasgrp2
Name: RAS, guanyl releasing protein 2
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to calcium ion and positive regulation of GTPase activity. Predicted to localize to the cytosol and plasma membrane. Used to study leukocyte adhesion deficiency 3. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 18. Is expressed in brain. Orthologous to human RASGRP2 (RAS guanyl releasing protein 2); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: calcium and DAG-regulated guanine nucleotide exchange factor I; CalDAG-GEFI; Caldaggef1; CDC25L; F25B3.3 kinase like protein; F25B3.3 kinase-like protein; RAP 1A protein-specific guanine nucleotide exchange factor 1; RAS guanyl-releasing protein 2
Orthologs:
Homo sapiens (human) : RASGRP2 (RAS guanyl releasing protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rasgrp2 (RAS guanyl releasing protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasgrp2 (RAS guanyl releasing protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RASGRP2 (RAS guanyl releasing protein 2)
Canis lupus familiaris (dog) : RASGRP2 (RAS guanyl releasing protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasgrp2 (RAS guanyl releasing protein 2)
Sus scrofa (pig) : RASGRP2 (RAS guanyl releasing protein 2)
Chlorocebus sabaeus (green monkey) : RASGRP2 (RAS guanyl releasing protein 2)
Heterocephalus glaber (naked mole-rat) : Rasgrp2 (RAS guanyl releasing protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,399,340 - 6,415,216 (+)Ensembl
GRCm38196,398,957 - 6,415,216 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,400,583 - 6,415,216 (+)NCBIGRCm37mm9NCBIm37
MGSCv36196,400,562 - 6,415,213 (+)NCBImm8
Celera196,273,600 - 6,288,233 (+)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rasgrp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1556892
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.