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Gene: H2-Ob (histocompatibility 2, O region beta locus) Mus musculus
Symbol: H2-Ob
Name: histocompatibility 2, O region beta locus
CRRD ID: 1556924
Description: Predicted to have MHC class II protein complex binding activity. Predicted to be involved in negative regulation of antigen processing and presentation of peptide antigen via MHC class II. Localizes to intracellular. Is expressed in hemolymphoid system and metanephros. Orthologous to human HLA-DOB (major histocompatibility complex, class II, DO beta); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A-bet; A-beta; A-beta-2; A-beta2; H-2; H-2Ab; H-2I; H-2O; H-2Ob; H2-A; H2-Ab; H2-Ab2; H2-IA; H2-IA-beta-2 antigen; H2-IAb2; MHC class II antigen O region beta locus isoform-003; O; Ob; vi; vic1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391734,457,879 - 34,464,882 (+)NCBI
GRCm381734,238,905 - 34,245,908 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,238,903 - 34,254,414 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,375,850 - 34,382,853 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,850,628 - 33,854,100 (+)NCBImm8
Celera1736,980,110 - 36,996,885 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on H2-Ob
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1556924
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.