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Gene: Leo1 (Leo1, Paf1/RNA polymerase II complex component) Mus musculus
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Symbol: Leo1
Name: Leo1, Paf1/RNA polymerase II complex component
Description: Predicted to have RNA polymerase II C-terminal domain phosphoserine binding activity. Involved in endodermal cell fate commitment and stem cell population maintenance. Predicted to localize to the Cdc73/Paf1 complex; centrosome; and fibrillar center. Is expressed in cerebral cortex; ovary; seminiferous cord; and telencephalon. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gm185; Leo1, Paf1/RNA polymerase II complex component, homolog; MGC100232; MGC102277; RNA polymerase-associated protein LEO1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl975,441,524 - 75,466,432 (+)Ensembl
GRCm38975,441,015 - 75,466,432 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37975,289,331 - 75,314,239 (+)NCBIGRCm37mm9NCBIm37
MGSCv36975,227,433 - 75,252,341 (+)NCBImm8
Celera972,601,044 - 72,627,947 (+)NCBICelera
Cytogenetic Map9 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Leo1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1556952
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.