Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Glis3 (GLIS family zinc finger 3) Mus musculus
Analyze
Symbol: Glis3
Name: GLIS family zinc finger 3
Description: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein which contains multiple C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the transcriptional regulation of insulin. It is thought to enhance GLI-RE-dependent transcription by binding to the GLI-RE consensus sequence (GACCACCCAC). Mutations in a similar gene in human have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4833409N03Rik; E230012L24; E330013K21Rik; GLI-similar 3; Kruppel-like zinc finger protein Glis3; zinc finger protein GLIS3
Orthologs:
Homo sapiens (human) : GLIS3 (GLIS family zinc finger 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Glis3 (GLIS family zinc finger 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glis3 (GLIS family zinc finger 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GLIS3 (GLIS family zinc finger 3)
Canis lupus familiaris (dog) : GLIS3 (GLIS family zinc finger 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glis3 (GLIS family zinc finger 3)
Sus scrofa (pig) : GLIS3 (GLIS family zinc finger 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381928,258,851 - 28,680,265 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371928,336,938 - 28,754,567 (-)NCBIGRCm37mm9NCBIm37
MGSCv361928,328,970 - 28,606,417 (-)NCBImm8
Celera1929,038,139 - 29,454,917 (-)NCBICelera
Cytogenetic Map19 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Glis3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557009
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.