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Gene: Kdm5b (lysine (K)-specific demethylase 5B) Mus musculus
Symbol: Kdm5b
Name: lysine (K)-specific demethylase 5B
CRRD ID: 1557118
Description: Exhibits histone demethylase activity (H3-K4 specific). Involved in several processes, including cellular response to leukemia inhibitory factor; mammary gland duct morphogenesis; and regulation of gene expression. Predicted to localize to cytosol and histone methyltransferase complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and malignant glioma. Orthologous to human KDM5B (lysine demethylase 5B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2010009J12Rik; 2210016I17Rik; [histone H3]-trimethyl-L-lysine(4) demethylase 5B; AW556288; D1Ertd202; D1Ertd202e; histone demethylase JARID1B; Jari; Jarid1b; jumonji, AT rich interactive domain 1B (Rbp2 like); jumonji/ARID domain-containing protein 1B; KIAA4034; lysine-specific demethylase 5B; mKIAA4034; Pl; PLU; PLU-1; Plu1; PUT1; putative DNA/chromatin binding motif 1; Rb-B; Rb-Bp2; RBBP2H1A
Homo sapiens (human) : KDM5B (lysine demethylase 5B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm5b (lysine demethylase 5B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5b (lysine demethylase 5B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5B (lysine demethylase 5B)
Canis lupus familiaris (dog) : KDM5B (lysine demethylase 5B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5b (lysine demethylase 5B)
Sus scrofa (pig) : KDM5B (lysine demethylase 5B)
Chlorocebus sabaeus (African green monkey) : KDM5B (lysine demethylase 5B)
Heterocephalus glaber (naked mole-rat) : Kdm5b (lysine demethylase 5B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391134,487,916 - 134,560,621 (+)NCBI
GRCm381134,560,178 - 134,632,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,560,171 - 134,635,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,456,755 - 136,529,455 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,376,606 - 136,449,288 (+)NCBImm8
Celera1137,167,324 - 137,243,758 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm5b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557118
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.