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Gene: Kdm5b (lysine (K)-specific demethylase 5B) Mus musculus
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Symbol: Kdm5b
Name: lysine (K)-specific demethylase 5B
CRRD ID: 1557118
Description: Exhibits histone demethylase activity (H3-K4 specific). Involved in several processes, including cellular response to leukemia inhibitory factor; mammary gland duct morphogenesis; and regulation of gene expression. Predicted to localize to cytosol and histone methyltransferase complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and malignant glioma. Orthologous to human KDM5B (lysine demethylase 5B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2010009J12Rik; 2210016I17Rik; [histone H3]-trimethyl-L-lysine(4) demethylase 5B; AW556288; D1Ertd202; D1Ertd202e; histone demethylase JARID1B; Jari; Jarid1b; jumonji, AT rich interactive domain 1B (Rbp2 like); jumonji/ARID domain-containing protein 1B; KIAA4034; lysine-specific demethylase 5B; mKIAA4034; Pl; PLU; PLU-1; Plu1; PUT1; putative DNA/chromatin binding motif 1; Rb-B; Rb-Bp2; RBBP2H1A
Orthologs:
Homo sapiens (human) : KDM5B (lysine demethylase 5B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm5b (lysine demethylase 5B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5b (lysine demethylase 5B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5B (lysine demethylase 5B)
Canis lupus familiaris (dog) : KDM5B (lysine demethylase 5B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5b (lysine demethylase 5B)
Sus scrofa (pig) : KDM5B (lysine demethylase 5B)
Chlorocebus sabaeus (African green monkey) : KDM5B (lysine demethylase 5B)
Heterocephalus glaber (naked mole-rat) : Kdm5b (lysine demethylase 5B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,487,916 - 134,560,621 (+)NCBI
GRCm381134,560,178 - 134,632,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,560,171 - 134,635,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,456,755 - 136,529,455 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,376,606 - 136,449,288 (+)NCBImm8
Celera1137,167,324 - 137,243,758 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm5b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557118
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.