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Gene: Spg11 (SPG11, spatacsin vesicle trafficking associated) Mus musculus
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Symbol: Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Description: Involved in several processes, including axon extension; phagosome-lysosome fusion involved in apoptotic cell clearance; and walking behavior. Localizes to several cellular components, including the axon; cytosol; and dendrite. Used to study hereditary spastic paraplegia 11. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin); INTERACTS WITH bisphenol A; dibutyl phthalate; N-ethyl-N-nitrosourea.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6030465E24Rik; A330015I11; C530005A01Rik; spastic paraplegia 11; spastic paraplegia 11 protein homolog; spatacsin
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382122,053,526 - 122,119,434 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372121,879,262 - 121,944,122 (-)NCBIGRCm37mm9NCBIm37
Celera2123,201,200 - 123,265,685 (-)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Spg11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557291
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.