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Gene: Brcc3 (BRCA1/BRCA2-containing complex, subunit 3) Mus musculus
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Symbol: Brcc3
Name: BRCA1/BRCA2-containing complex, subunit 3
Description: Predicted to have enzyme regulator activity; peptidase activity, acting on L-amino acid peptides; and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including histone H2A K63-linked deubiquitination; response to X-ray; and signal transduction involved in G2 DNA damage checkpoint. Predicted to localize to the cytoplasm and nucleus. Is expressed in bladder; male associated reproductive structure; testis; ureter; and urethra of male. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6.1A protein; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; C6.1A; lys-63-specific deubiquitinase BRCC36; MGC29148
Orthologs:
Homo sapiens (human) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Brcc3 (BRCA1/BRCA2-containing complex, subunit 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brcc3 (BRCA1/BRCA2-containing complex subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)
Canis lupus familiaris (dog) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brcc3 (BRCA1/BRCA2-containing complex subunit 3)
Sus scrofa (pig) : BRCC3 (BRCA1/BRCA2-containing complex subunit 3)
more info ...
Related Pseudogenes: Gm12598   Gm18884  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38X75,416,628 - 75,455,702 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X72,661,967 - 72,701,040 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X71,669,420 - 71,706,717 (+)NCBImm8
CeleraX66,818,616 - 66,858,058 (+)NCBICelera
Cytogenetic MapX A7.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Brcc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557359
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.