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Gene: G3bp1 (GTPase activating protein (SH3 domain) binding protein 1) Mus musculus
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Symbol: G3bp1
Name: GTPase activating protein (SH3 domain) binding protein 1
Description: Exhibits mRNA binding activity. Involved in negative regulation of canonical Wnt signaling pathway. Localizes to cytoplasmic stress granule. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human G3BP1 (G3BP stress granule assembly factor 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AI849976; ATP-dependent DNA helicase VIII; B430204O07; C87777; G3bp; G3BP-1; GAP SH3 binding protein; GAP SH3 domain-binding protein 1; HDH-VIII; KIAA4115; mKIAA4115; ras GTPase-activating protein-binding protein 1; Ras-GTPase-activating protein SH3-domain binding protein 1; RP23-336J1.4
Orthologs:
Homo sapiens (human) : G3BP1 (G3BP stress granule assembly factor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : G3bp1 (G3BP stress granule assembly factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G3bp1 (G3BP stress granule assembly factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : G3BP1 (G3BP stress granule assembly factor 1)
Canis lupus familiaris (dog) : G3BP1 (G3BP stress granule assembly factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G3bp1 (G3BP stress granule assembly factor 1)
Sus scrofa (pig) : G3BP1 (G3BP stress granule assembly factor 1)
Chlorocebus sabaeus (African green monkey) : G3BP1 (G3BP stress granule assembly factor 1)
Heterocephalus glaber (naked mole-rat) : G3bp1 (G3BP stress granule assembly factor 1)
more info ...
Related Pseudogenes: Gm14896   Gm5913   Gm7405   Gm9509  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1155,469,685 - 55,504,838 (+)EnsemblGRCm38mm10GRCm38
GRCm381155,469,657 - 55,500,888 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371155,283,254 - 55,314,389 (+)NCBIGRCm37mm9NCBIm37
MGSCv361155,313,175 - 55,344,310 (+)NCBImm8
Celera1160,271,641 - 60,286,911 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on G3bp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557408
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.