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Gene: Ubqln2 (ubiquilin 2) Mus musculus
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Symbol: Ubqln2
Name: ubiquilin 2
Description: Predicted to have polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including negative regulation of receptor-mediated endocytosis; regulation of cellular catabolic process; and ubiquitin-dependent ERAD pathway. Predicted to localize to cytosol and plasma membrane. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and amyotrophic lateral sclerosis type 15. Orthologous to human UBQLN2 (ubiquilin 2); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH bisphenol A; buta-1,3-diene; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Chap1; Dsk2; DSK2 homolog; HRIHFB2157; Plic-2; Plic2; protein linking IAP with cytoskeleton 2; ubiquilin-2; ubiquitin-like product Chap1/Dsk2; Ubiquitin-related protein
Orthologs:
Homo sapiens (human) : UBQLN2 (ubiquilin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ubqln2 (ubiquilin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ubqln2 (ubiquilin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : UBQLN2 (ubiquilin 2)
Canis lupus familiaris (dog) : UBQLN2 (ubiquilin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ubqln2 (ubiquilin 2)
Sus scrofa (pig) : UBQLN2 (ubiquilin 2)
Chlorocebus sabaeus (African green monkey) : UBQLN2 (ubiquilin 2)
Heterocephalus glaber (naked mole-rat) : Ubqln2 (ubiquilin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 EnsemblX153,498,227 - 153,501,570 (+)EnsemblGRCm38mm10GRCm38
GRCm38X153,498,232 - 153,501,562 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X149,932,775 - 149,936,105 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X148,838,948 - 148,842,278 (+)NCBImm8
CeleraX135,753,727 - 135,757,059 (-)NCBICelera
Cytogenetic MapXF3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ubqln2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557414
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.