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Gene: Gdf3 (growth differentiation factor 3) Mus musculus
Symbol: Gdf3
Name: growth differentiation factor 3
Description: Predicted to have cytokine activity; protein kinase binding activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including anterior/posterior axis specification; negative regulation of myoblast differentiation; and positive regulation of fat cell differentiation. Predicted to localize to the cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in Klippel-Feil syndrome and isolated microphthalmia 7. Is expressed in several structures, including brain; epiblast; and skeleton. Orthologous to human GDF3 (growth differentiation factor 3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C78318; ecat9; Gdf-3; growth/differentiation factor 3; MGC123990; MGC123991; VG-1-related protein 2; Vgr-2; Vgr2
Homo sapiens (human) : GDF3 (growth differentiation factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gdf3 (growth differentiation factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gdf3 (growth differentiation factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GDF3 (growth differentiation factor 3)
Canis lupus familiaris (dog) : GDF3 (growth differentiation factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gdf3 (growth differentiation factor 3)
Sus scrofa (pig) : GDF3 (growth differentiation factor 3)
Chlorocebus sabaeus (African green monkey) : GDF3 (growth differentiation factor 3)
Heterocephalus glaber (naked mole-rat) : Gdf3 (growth differentiation factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6122,605,403 - 122,610,087 (-)Ensembl
GRCm386122,605,403 - 122,610,087 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376122,555,421 - 122,560,089 (-)NCBIGRCm37mm9NCBIm37
MGSCv366122,571,022 - 122,575,690 (-)NCBImm8
Celera6124,400,537 - 124,405,205 (-)NCBICelera
Cytogenetic Map6 F1NCBI
cM Map657.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gdf3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557417
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.