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Gene: Rc3h1 (RING CCCH (C3H) domains 1) Mus musculus
Symbol: Rc3h1
Name: RING CCCH (C3H) domains 1
Description: Exhibits RNA binding activity and zinc ion binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; lymphocyte homeostasis; and negative regulation of lymphocyte activation. Localizes to P-body and cytoplasmic stress granule. Used to study peripheral T-cell lymphoma and systemic lupus erythematosus. Orthologous to human RC3H1 (ring finger and CCCH-type domains 1); INTERACTS WITH 1,2-dichloroethane; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730557L09Rik; Gm551; mKIAA2025; N28103; probable E3 ubiquitin-protein ligase Roquin; protein Sanroque; RIKEN cDNA 5730557L09 gene; RING finger and C3H zinc finger protein 1; RING finger and CCCH-type zinc finger domain-containing protein 1; roquin; roquin-1
Homo sapiens (human) : RC3H1 (ring finger and CCCH-type domains 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rc3h1 (ring finger and CCCH-type domains 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rc3h1 (ring finger and CCCH-type domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RC3H1 (ring finger and CCCH-type domains 1)
Canis lupus familiaris (dog) : RC3H1 (ring finger and CCCH-type domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rc3h1 (ring finger and CCCH-type domains 1)
Sus scrofa (pig) : RC3H1 (ring finger and CCCH-type domains 1)
Chlorocebus sabaeus (African green monkey) : RC3H1 (ring finger and CCCH-type domains 1)
Heterocephalus glaber (naked mole-rat) : Rc3h1 (ring finger and CCCH-type domains 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1160,906,418 - 160,974,978 (+)EnsemblGRCm38mm10GRCm38
GRCm381160,906,411 - 160,974,976 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371162,836,542 - 162,905,107 (+)NCBIGRCm37mm9NCBIm37
MGSCv361162,743,147 - 162,804,531 (+)NCBImm8
Celera1163,345,875 - 163,414,502 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rc3h1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557447
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.