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Gene: Trpm7 (transient receptor potential cation channel, subfamily M, member 7) Mus musculus
Symbol: Trpm7
Name: transient receptor potential cation channel, subfamily M, member 7
Description: Exhibits calcium channel activity; cytoskeletal protein binding activity; and kinase activity. Involved in several processes, including actomyosin structure organization; calcium-dependent cell-matrix adhesion; and protein autophosphorylation. Localizes to the plasma membrane and ruffle. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1. Is expressed in cochlea; dorsal root ganglion; inferior vagus ganglion; vagus ganglion; and vibrissa. Orthologous to human TRPM7 (transient receptor potential cation channel subfamily M member 7); INTERACTS WITH 3,3',4,4'-tetrachlorobiphenyl; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310022G15Rik; 4833414K03Rik; 5033407O22Rik; CHAK; CHAK1; channel-kinase 1; long transient receptor potential channel 7; Ltpr7; LTrpC-7; Ltrpc7; transient receptor potential cation channel subfamily M member 7; transient receptor potential M7; transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-related protein, ChaK; TRPPLIK
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382126,791,558 - 126,876,261 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372126,617,294 - 126,701,997 (-)NCBIGRCm37mm9NCBIm37
MGSCv362126,483,006 - 126,567,652 (-)NCBImm8
Celera2128,031,446 - 128,117,211 (-)NCBICelera
Cytogenetic Map2 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Trpm7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557461
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.