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Gene: Plcb2 (phospholipase C, beta 2) Mus musculus
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Symbol: Plcb2
Name: phospholipase C, beta 2
Description: Predicted to have G-protein beta/gamma-subunit complex binding activity; phosphatidylinositol phospholipase C activity; and phospholipid binding activity. Involved in sensory perception of bitter taste. Localizes to the cytoplasm. Is expressed in several structures, including early conceptus; genitourinary system; gut; immune system; and liver. Orthologous to human PLCB2 (phospholipase C beta 2); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dextran sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; AI550384; B230205M18Rik; B230399N12; phosphoinositide phospholipase C-beta-2; phospholipase C-beta-2; PLC-beta-2
Orthologs:
Homo sapiens (human) : PLCB2 (phospholipase C beta 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plcb2 (phospholipase C, beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb2 (phospholipase C beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB2 (phospholipase C beta 2)
Canis lupus familiaris (dog) : PLCB2 (phospholipase C beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb2 (phospholipase C beta 2)
Sus scrofa (pig) : PLCB2 (phospholipase C beta 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382118,705,003 - 118,728,661 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372118,533,253 - 118,554,174 (-)NCBIGRCm37mm9NCBIm37
MGSCv362118,398,958 - 118,419,879 (-)NCBImm8
Celera2119,861,823 - 119,882,734 (-)NCBICelera
Cytogenetic Map2 E5NCBI
cM Map259.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Plcb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557476
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.