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Gene: Eda (ectodysplasin-A) Mus musculus
Symbol: Eda
Name: ectodysplasin-A
CRRD ID: 1557590
Description: Predicted to have death receptor agonist activity and death receptor binding activity. Involved in several processes, including animal organ development; cell-matrix adhesion; and positive regulation of signal transduction. Localizes to apical part of cell; endoplasmic reticulum membrane; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; cornea epithelium; future brain; and skin. Used to study hypohidrotic ectodermal dysplasia. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Orthologous to human EDA (ectodysplasin A); INTERACTS WITH 4,4'-sulfonyldiphenol; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ed1; EDA protein homolog; Eda-; Eda-A1; Eda-A2; EDA1; HED; Ta; tabby; Tnlg7c; tumor necrosis factor ligand 7c; XLHED
Homo sapiens (human) : EDA (ectodysplasin A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Eda (ectodysplasin-A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eda (ectodysplasin A)
Pan paniscus (bonobo/pygmy chimpanzee) : EDA (ectodysplasin A)
Canis lupus familiaris (dog) : EDA (ectodysplasin A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101956136 (ectodysplasin-A)
Sus scrofa (pig) : EDA (ectodysplasin A)
Chlorocebus sabaeus (African green monkey) : EDA (ectodysplasin A)
Heterocephalus glaber (naked mole-rat) : Eda (ectodysplasin A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39X99,019,212 - 99,444,366 (+)NCBI
GRCm38X99,975,606 - 100,400,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX99,975,606 - 100,400,762 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X97,170,945 - 97,596,099 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X82,816,290 - 83,239,228 (+)NCBImm8
MGSCv36X96,178,325 - 96,603,479 (+)NCBImm8
CeleraX86,912,424 - 87,326,326 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Eda
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557590
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.