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Gene: Eda (ectodysplasin-A) Mus musculus
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Symbol: Eda
Name: ectodysplasin-A
CRRD ID: 1557590
Description: Predicted to have death receptor agonist activity and death receptor binding activity. Involved in several processes, including animal organ development; cell-matrix adhesion; and positive regulation of signal transduction. Localizes to apical part of cell; endoplasmic reticulum membrane; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; cornea epithelium; future brain; and skin. Used to study hypohidrotic ectodermal dysplasia. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Orthologous to human EDA (ectodysplasin A); INTERACTS WITH 4,4'-sulfonyldiphenol; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ed1; EDA protein homolog; Eda-; Eda-A1; Eda-A2; EDA1; HED; Ta; tabby; Tnlg7c; tumor necrosis factor ligand 7c; XLHED
Orthologs:
Homo sapiens (human) : EDA (ectodysplasin A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Eda (ectodysplasin-A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eda (ectodysplasin A)
Pan paniscus (bonobo/pygmy chimpanzee) : EDA (ectodysplasin A)
Canis lupus familiaris (dog) : EDA (ectodysplasin A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101956136 (ectodysplasin-A)
Sus scrofa (pig) : EDA (ectodysplasin A)
Chlorocebus sabaeus (African green monkey) : EDA (ectodysplasin A)
Heterocephalus glaber (naked mole-rat) : Eda (ectodysplasin A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X99,019,212 - 99,444,366 (+)NCBI
GRCm38X99,975,606 - 100,400,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX99,975,606 - 100,400,762 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X97,170,945 - 97,596,099 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X82,816,290 - 83,239,228 (+)NCBImm8
MGSCv36X96,178,325 - 96,603,479 (+)NCBImm8
CeleraX86,912,424 - 87,326,326 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX43.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Eda
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557590
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.