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Gene: Msr1 (macrophage scavenger receptor 1) Mus musculus
Symbol: Msr1
Name: macrophage scavenger receptor 1
Description: Exhibits amyloid-beta binding activity; cargo receptor activity; and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis; lipoprotein transport; and positive regulation of cholesterol storage. Localizes to plasma membrane. Is expressed in several structures, including alimentary system; limb; neural tube; reproductive system; and yolk sac. Human ortholog(s) of this gene implicated in Barrett's esophagus; arteriosclerosis; and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: macrophage acetylated LDL receptor I and II; macrophage scavenger receptor types I and II; MRS-A; MSR; MSR-A; Scara1; scavenger receptor type A; Scvr; SR-A; SR-AI; SR-AII
Homo sapiens (human) : MSR1 (macrophage scavenger receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Msr1 (macrophage scavenger receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msr1 (macrophage scavenger receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MSR1 (macrophage scavenger receptor 1)
Canis lupus familiaris (dog) : MSR1 (macrophage scavenger receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msr1 (macrophage scavenger receptor 1)
Sus scrofa (pig) : MSR1 (macrophage scavenger receptor 1)
Chlorocebus sabaeus (African green monkey) : MSR1 (macrophage scavenger receptor 1)
Heterocephalus glaber (naked mole-rat) : Msr1 (macrophage scavenger receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl839,581,685 - 39,642,673 (-)EnsemblGRCm38mm10GRCm38
GRCm38839,543,232 - 39,642,750 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37840,667,054 - 40,728,032 (-)NCBIGRCm37mm9NCBIm37
MGSCv36841,102,269 - 41,141,495 (-)NCBImm8
Celera842,254,529 - 42,315,500 (-)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Msr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557852
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.