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Gene: Msr1 (macrophage scavenger receptor 1) Mus musculus
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Symbol: Msr1
Name: macrophage scavenger receptor 1
Description: Exhibits amyloid-beta binding activity; cargo receptor activity; and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis; lipoprotein transport; and positive regulation of cholesterol storage. Localizes to plasma membrane. Is expressed in several structures, including alimentary system; limb; neural tube; reproductive system; and yolk sac. Human ortholog(s) of this gene implicated in Barrett's esophagus; arteriosclerosis; and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: macrophage acetylated LDL receptor I and II; macrophage scavenger receptor types I and II; MRS-A; MSR; MSR-A; Scara1; scavenger receptor type A; Scvr; SR-A; SR-AI; SR-AII
Orthologs:
Homo sapiens (human) : MSR1 (macrophage scavenger receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Msr1 (macrophage scavenger receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msr1 (macrophage scavenger receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MSR1 (macrophage scavenger receptor 1)
Canis lupus familiaris (dog) : MSR1 (macrophage scavenger receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msr1 (macrophage scavenger receptor 1)
Sus scrofa (pig) : MSR1 (macrophage scavenger receptor 1)
Chlorocebus sabaeus (African green monkey) : MSR1 (macrophage scavenger receptor 1)
Heterocephalus glaber (naked mole-rat) : Msr1 (macrophage scavenger receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl839,581,685 - 39,642,673 (-)EnsemblGRCm38mm10GRCm38
GRCm38839,543,232 - 39,642,750 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37840,667,054 - 40,728,032 (-)NCBIGRCm37mm9NCBIm37
MGSCv36841,102,269 - 41,141,495 (-)NCBImm8
Celera842,254,529 - 42,315,500 (-)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Msr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557852
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.