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Gene: Dlx6 (distal-less homeobox 6) Mus musculus
Symbol: Dlx6
Name: distal-less homeobox 6
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of epithelial cell proliferation; and roof of mouth development. Predicted to localize to the nucleus. Used to study split hand-foot malformation 1. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb ectoderm; and sensory organ. Orthologous to human DLX6 (distal-less homeobox 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeobox protein DLX-6
Homo sapiens (human) : DLX6 (distal-less homeobox 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dlx6 (distal-less homeobox 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlx6 (distal-less homeobox 6)
Canis lupus familiaris (dog) : DLX6 (distal-less homeobox 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlx6 (distal-less homeobox 6)
Sus scrofa (pig) : DLX6 (distal-less homeobox 6)
Chlorocebus sabaeus (green monkey) : DLX6 (distal-less homeobox 6)
Heterocephalus glaber (naked mole-rat) : Dlx6 (distal-less homeobox 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl66,863,334 - 6,868,568 (+)Ensembl
GRCm3866,863,334 - 6,867,970 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3766,813,334 - 6,817,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv3666,815,619 - 6,820,850 (+)NCBImm8
Celera67,009,721 - 7,013,403 (+)NCBICelera
Cytogenetic Map6 A1NCBI
cM Map62.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dlx6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557991
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.