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Gene: Dlx6 (distal-less homeobox 6) Mus musculus
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Symbol: Dlx6
Name: distal-less homeobox 6
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including embryonic morphogenesis; positive regulation of epithelial cell proliferation; and roof of mouth development. Predicted to localize to the nucleus. Used to study split hand-foot malformation 1. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb ectoderm; and sensory organ. Orthologous to human DLX6 (distal-less homeobox 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeobox protein DLX-6
Orthologs:
Homo sapiens (human) : DLX6 (distal-less homeobox 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dlx6 (distal-less homeobox 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlx6 (distal-less homeobox 6)
Canis lupus familiaris (dog) : DLX6 (distal-less homeobox 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlx6 (distal-less homeobox 6)
Sus scrofa (pig) : DLX6 (distal-less homeobox 6)
Chlorocebus sabaeus (green monkey) : DLX6 (distal-less homeobox 6)
Heterocephalus glaber (naked mole-rat) : Dlx6 (distal-less homeobox 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl66,863,334 - 6,868,568 (+)Ensembl
GRCm3866,863,334 - 6,867,970 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3766,813,334 - 6,817,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv3666,815,619 - 6,820,850 (+)NCBImm8
Celera67,009,721 - 7,013,403 (+)NCBICelera
Cytogenetic Map6 A1NCBI
cM Map62.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dlx6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1557991
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.