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Gene: Hspa1a (heat shock protein 1A) Mus musculus
Symbol: Hspa1a
Name: heat shock protein 1A
CRRD ID: 1558069
Description: Exhibits protein folding chaperone. Involved in several processes, including DNA metabolic process; lysosomal transport; and response to heat. Localizes to cytoplasm. Predicted to colocalize with COP9 signalosome. Is expressed in several structures, including adrenal gland; early conceptus; genitourinary system; and vibrissa. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1B (heat shock protein family A (Hsp70) member 1B); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 68 kDa heat shock protein; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 3; heat shock 70kDa protein 1A; heat shock protein, 70 kDa 3; Hsp; hsp68; Hsp7; Hsp70; Hsp70-3; Hsp70.3; hsp70A1; Hsp72; inducible heat shock protein 70; MGC189852
Homo sapiens (human) : HSPA1A (heat shock protein family A (Hsp70) member 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hspa1a (heat shock protein family A (Hsp70) member 1A)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HSPA1A (heat shock protein family A (Hsp70) member 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa1a (heat shock protein family A (Hsp70) member 1A)
Chlorocebus sabaeus (African green monkey) : HSPA1A (heat shock protein family A (Hsp70) member 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391735,188,335 - 35,191,132 (-)NCBI
GRCm381734,969,359 - 34,972,156 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,969,190 - 34,972,156 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,106,304 - 35,109,101 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,577,246 - 34,580,180 (-)NCBImm8
Celera1738,065,583 - 38,068,380 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hspa1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558069
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.