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Gene: Hdac8 (histone deacetylase 8) Mus musculus
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Symbol: Hdac8
Name: histone deacetylase 8
Description: Predicted to have several functions, including chromatin binding activity; heat shock protein binding activity; and histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of protein ubiquitination; and regulation of chromosome organization. Predicted to localize to the histone deacetylase complex and plasma membrane. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Is expressed in 2-cell stage embryo; foregut; retina; and ventricular layer. Orthologous to human HDAC8 (histone deacetylase 8); PARTICIPATES IN histone modification pathway; INTERACTS WITH 3,3'-diindolylmethane; bis(2-chloroethyl) sulfide; indole-3-methanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610007D20Rik; HD8
Orthologs:
Homo sapiens (human) : HDAC8 (histone deacetylase 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac8 (histone deacetylase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac8 (histone deacetylase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC8 (histone deacetylase 8)
Canis lupus familiaris (dog) : HDAC8 (histone deacetylase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac8 (histone deacetylase 8)
Sus scrofa (pig) : HDAC8 (histone deacetylase 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38X102,284,638 - 102,505,381 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X99,479,979 - 99,700,487 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X98,487,359 - 98,707,867 (-)NCBImm8
CeleraX89,195,856 - 89,416,063 (-)NCBICelera
Cytogenetic MapX DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hdac8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558090
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.