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Gene: Hdac8 (histone deacetylase 8) Mus musculus
Symbol: Hdac8
Name: histone deacetylase 8
Description: Predicted to have several functions, including chromatin binding activity; heat shock protein binding activity; and histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of protein ubiquitination; and regulation of chromosome organization. Predicted to localize to the histone deacetylase complex and plasma membrane. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Is expressed in 2-cell stage embryo; foregut; retina; and ventricular layer. Orthologous to human HDAC8 (histone deacetylase 8); PARTICIPATES IN histone modification pathway; INTERACTS WITH 3,3'-diindolylmethane; bis(2-chloroethyl) sulfide; indole-3-methanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610007D20Rik; HD8
Homo sapiens (human) : HDAC8 (histone deacetylase 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hdac8 (histone deacetylase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac8 (histone deacetylase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC8 (histone deacetylase 8)
Canis lupus familiaris (dog) : HDAC8 (histone deacetylase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac8 (histone deacetylase 8)
Sus scrofa (pig) : HDAC8 (histone deacetylase 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38X102,284,638 - 102,505,381 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X99,479,979 - 99,700,487 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X98,487,359 - 98,707,867 (-)NCBImm8
CeleraX89,195,856 - 89,416,063 (-)NCBICelera
Cytogenetic MapX DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hdac8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558090
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.