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Gene: Blnk (B cell linker) Mus musculus
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Symbol: Blnk
Name: B cell linker
Description: Predicted to be involved in intracellular signal transduction and transmembrane receptor protein tyrosine kinase signaling pathway. Localizes to cytoplasm. Is expressed in several structures, including genitourinary system; gut; immune system; lung; and olfactory epithelium. Human ortholog(s) of this gene implicated in agammaglobulinemia and agammaglobulinemia 4. Orthologous to human BLNK (B cell linker); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; B cell receptor signaling pathway; primary immunodeficiency pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; BASH; Bca; cytoplasmic adapter protein; Ly-57; Ly57; lymphocyte antigen 57; Lyw-57; SLP-65; src homology 2 domain-containing leukocyte protein of 65 kDa
Orthologs:
Homo sapiens (human) : BLNK (B cell linker)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Blnk (B-cell linker)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Blnk (B cell linker)
Pan paniscus (bonobo/pygmy chimpanzee) : BLNK (B cell linker)
Canis lupus familiaris (dog) : BLNK (B cell linker)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Blnk (B cell linker)
Sus scrofa (pig) : BLNK (B cell linker)
Chlorocebus sabaeus (African green monkey) : BLNK (B cell linker)
Heterocephalus glaber (naked mole-rat) : Blnk (B cell linker)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1940,928,927 - 40,994,535 (-)EnsemblGRCm38mm10GRCm38
GRCm381940,928,927 - 40,994,221 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371941,003,417 - 41,069,025 (-)NCBIGRCm37mm9NCBIm37
MGSCv361940,982,238 - 41,047,846 (-)NCBImm8
Celera1941,731,720 - 41,797,451 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1934.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Blnk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558103
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.