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Gene: Lrsam1 (leucine rich repeat and sterile alpha motif containing 1) Mus musculus
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Symbol: Lrsam1
Name: leucine rich repeat and sterile alpha motif containing 1
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in several processes, including positive regulation of macroautophagy; protein ubiquitination; and ubiquitin-dependent endocytosis. Predicted to localize to the cytosol and membrane. Used to study Charcot-Marie-Tooth disease axonal type 2P. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2P. Is expressed in cranial ganglion; dorsal root ganglion; hindbrain; and olfactory epithelium. Orthologous to human LRSAM1 (leucine rich repeat and sterile alpha motif containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase LRSAM1; leucine-rich repeat and sterile alpha motif-containing protein 1; MGC56830; RING-type E3 ubiquitin transferase LRSAM1; tsg101-associated ligase
Orthologs:
Related Pseudogenes: 4930555K19Rik  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38232,925,215 - 32,961,668 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37232,780,740 - 32,816,771 (-)NCBIGRCm37mm9NCBIm37
MGSCv36232,747,229 - 32,783,260 (-)NCBImm8
Celera232,632,197 - 32,668,237 (-)NCBICelera
Cytogenetic Map2 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lrsam1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558134
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.