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Gene: Mmut (methylmalonyl-Coenzyme A mutase) Mus musculus
Symbol: Mmut
Name: methylmalonyl-Coenzyme A mutase
CRRD ID: 1558195
Description: Exhibits methylmalonyl-CoA mutase activity. Involved in post-embryonic development. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; lung; nervous system; and trophectoderm. Used to study methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency. Human ortholog(s) of this gene implicated in methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency. Orthologous to human MMUT (methylmalonyl-CoA mutase); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D230010K02Rik; Mcm; methylmalonyl-CoA isomerase; methylmalonyl-CoA mutase, mitochondrial; Mut
Homo sapiens (human) : MMUT (methylmalonyl-CoA mutase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mmut (methylmalonyl-CoA mutase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmut (methylmalonyl-CoA mutase)
Pan paniscus (bonobo/pygmy chimpanzee) : MMUT (methylmalonyl-CoA mutase)
Canis lupus familiaris (dog) : MMUT (methylmalonyl-CoA mutase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmut (methylmalonyl-CoA mutase)
Sus scrofa (pig) : MMUT (methylmalonyl-CoA mutase)
Chlorocebus sabaeus (African green monkey) : MMUT (methylmalonyl-CoA mutase)
Heterocephalus glaber (naked mole-rat) : Mmut (methylmalonyl-CoA mutase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391741,245,576 - 41,272,880 (+)NCBI
GRCm381740,934,685 - 40,961,990 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1740,934,685 - 40,961,988 (+)EnsemblGRCm38mm10GRCm38
MGSCv371741,071,634 - 41,098,938 (+)NCBIGRCm37mm9NCBIm37
MGSCv361740,398,258 - 40,425,133 (+)NCBImm8
Celera1744,347,903 - 44,375,209 (+)NCBICelera
Cytogenetic Map17B2NCBI
cM Map1719.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mmut
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558195
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.