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Gene: Irf3 (interferon regulatory factor 3) Mus musculus
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Symbol: Irf3
Name: interferon regulatory factor 3
CRRD ID: 1558245
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to other organism; regulation of defense response; and regulation of type I interferon production. Localizes to cytoplasm and nucleus. Is expressed in several structures, including early conceptus; eye; genitourinary system; and telencephalon. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human IRF3 (interferon regulatory factor 3); PARTICIPATES IN Toll-like receptor signaling pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-phenylprop-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C920001K05Rik; IRF; IRF-3; MGC91046
Orthologs:
Homo sapiens (human) : IRF3 (interferon regulatory factor 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Irf3 (interferon regulatory factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irf3 (interferon regulatory factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : IRF3 (interferon regulatory factor 3)
Canis lupus familiaris (dog) : IRF3 (interferon regulatory factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irf3 (interferon regulatory factor 3)
Sus scrofa (pig) : IRF3 (interferon regulatory factor 3)
Chlorocebus sabaeus (African green monkey) : IRF3 (interferon regulatory factor 3)
Heterocephalus glaber (naked mole-rat) : Irf3 (interferon regulatory factor 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,647,072 - 44,652,272 (+)NCBI
GRCm38744,997,648 - 45,002,848 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,997,648 - 45,002,848 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,253,030 - 52,258,218 (+)NCBIGRCm37mm9NCBIm37
MGSCv36744,865,702 - 44,870,890 (+)NCBImm8
Celera740,449,220 - 40,454,417 (+)NCBICelera
Cytogenetic Map7B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Irf3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558245
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.