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Gene: H2-Ea (histocompatibility 2, class II antigen E alpha) Mus musculus
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Symbol: H2-Ea
Name: histocompatibility 2, class II antigen E alpha
Description: Human ortholog(s) of this gene implicated in Parkinson's disease (multiple); allergic hypersensitivity disease; asthma; and autoimmune hypersensitivity disease (multiple). Orthologous to human HLA-DRA (major histocompatibility complex, class II, DR alpha).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323765; E-alpha-f; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2Ea; H2-Ea-ps; H2-IE-alpha; histocompatibility 2, class II antigen E alpha, pseudogene; HLA class II histocompatibility antigen, DR alpha chain; I-E alpha MHC class II; I-Ealpha; Ia-3; Ia3; MGC117888; MHC class II alpha chain; MHC class II antigen E alpha; MHC class II antigen IEk-alpha; MHC class II H2-E alpha chain; MHC class II protein; MHC-H2-Ea
Orthologs:
Homo sapiens (human) : HLA-DRA (major histocompatibility complex, class II, DR alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : RT1-Da (RT1 class II, locus Da)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102019320 (mamu class II histocompatibility antigen, DR alpha chain)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100987081 (HLA class II histocompatibility antigen, DR alpha chain)
Canis lupus familiaris (dog) : DLA-DRA (MHC class II DR alpha chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969065 (mamu class II histocompatibility antigen, DR alpha chain)
Sus scrofa (pig) : SLA-DRA (MHC class II DR-alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381734,341,959 - 34,347,547 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,478,902 - 34,484,492 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,479,157 - 34,481,590 (-)NCBImm8
Celera1737,104,259 - 37,109,038 (-)NCBICelera
Cytogenetic Map17 B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on H2-Ea
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558302
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.