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Gene: Lama4 (laminin, alpha 4) Mus musculus
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Symbol: Lama4
Name: laminin, alpha 4
Description: Predicted to have extracellular matrix structural constituent and signaling receptor binding activity. Involved in blood vessel development; brown fat cell differentiation; and negative regulation of cold-induced thermogenesis. Localizes to the basement membrane; neuromuscular junction; and synaptic cleft. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1JJ. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; nervous system; and sensory organ. Orthologous to human LAMA4 (laminin subunit alpha 4); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; sleeping sickness pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: laminin [a]4; laminin subunit alpha-4; laminin-14 subunit alpha; laminin-8 subunit alpha; laminin-9 subunit alpha; MGC141567
Orthologs:
Homo sapiens (human) : LAMA4 (laminin subunit alpha 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lama4 (laminin subunit alpha 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama4 (laminin subunit alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMA4 (laminin subunit alpha 4)
Canis lupus familiaris (dog) : LAMA4 (laminin subunit alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama4 (laminin subunit alpha 4)
Sus scrofa (pig) : LAMA4 (laminin subunit alpha 4)
Chlorocebus sabaeus (African green monkey) : LAMA4 (laminin subunit alpha 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1038,965,515 - 39,110,188 (+)Ensembl
GRCm381038,965,515 - 39,110,188 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371038,685,647 - 38,829,937 (+)NCBIGRCm37mm9NCBIm37
MGSCv361038,642,372 - 38,799,589 (+)NCBImm8
Celera1039,849,203 - 39,994,405 (+)NCBICelera
Cytogenetic Map10 B1NCBI
cM Map1020.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lama4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558366
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.