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Gene: Lama4 (laminin, alpha 4) Mus musculus
Symbol: Lama4
Name: laminin, alpha 4
Description: Predicted to have extracellular matrix structural constituent and signaling receptor binding activity. Involved in blood vessel development; brown fat cell differentiation; and negative regulation of cold-induced thermogenesis. Localizes to the basement membrane; neuromuscular junction; and synaptic cleft. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1JJ. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; nervous system; and sensory organ. Orthologous to human LAMA4 (laminin subunit alpha 4); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; sleeping sickness pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: laminin [a]4; laminin subunit alpha-4; laminin-14 subunit alpha; laminin-8 subunit alpha; laminin-9 subunit alpha; MGC141567
Homo sapiens (human) : LAMA4 (laminin subunit alpha 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lama4 (laminin subunit alpha 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lama4 (laminin subunit alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMA4 (laminin subunit alpha 4)
Canis lupus familiaris (dog) : LAMA4 (laminin subunit alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lama4 (laminin subunit alpha 4)
Sus scrofa (pig) : LAMA4 (laminin subunit alpha 4)
Chlorocebus sabaeus (African green monkey) : LAMA4 (laminin subunit alpha 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1038,965,515 - 39,110,188 (+)Ensembl
GRCm381038,965,515 - 39,110,188 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371038,685,647 - 38,829,937 (+)NCBIGRCm37mm9NCBIm37
MGSCv361038,642,372 - 38,799,589 (+)NCBImm8
Celera1039,849,203 - 39,994,405 (+)NCBICelera
Cytogenetic Map10 B1NCBI
cM Map1020.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lama4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558366
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.