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Gene: Flrt3 (fibronectin leucine rich transmembrane protein 3) Mus musculus
Symbol: Flrt3
Name: fibronectin leucine rich transmembrane protein 3
Description: Exhibits chemorepellent activity and fibroblast growth factor receptor binding activity. Involved in several processes, including nervous system development; proepicardium cell migration involved in pericardium morphogenesis; and synaptic membrane adhesion. Localizes to several cellular components, including the axonal growth cone; glutamatergic synapse; and integral component of postsynaptic membrane. Colocalizes with the focal adhesion. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 21 with or without anosmia. Is expressed in several structures, including brain; embryo ectoderm; embryo mesenchyme; jaw; and sensory organ. Orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5530600M07Rik; C430047I10Rik; leucine-rich repeat transmembrane protein FLRT3; mKIAA1469
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382140,658,198 - 140,671,476 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372140,483,934 - 140,497,212 (-)NCBIGRCm37mm9NCBIm37
MGSCv362140,349,640 - 140,362,910 (-)NCBImm8
Celera2141,850,226 - 141,863,510 (-)NCBICelera
Cytogenetic Map2 F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Flrt3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558376
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.