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Gene: Cyp2c40 (cytochrome P450, family 2, subfamily c, polypeptide 40) Mus musculus
Symbol: Cyp2c40
Name: cytochrome P450, family 2, subfamily c, polypeptide 40
Description: Exhibits arachidonic acid 14,15-epoxygenase activity. Predicted to be involved in several processes, including epoxygenase P450 pathway; exogenous drug catabolic process; and xenobiotic metabolic process. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle. Is expressed in embryo; liver; and metanephros. Human ortholog(s) of this gene implicated in several diseases, including eosinophilic esophagitis; glucose metabolism disease (multiple); multiple myeloma; sickle cell anemia; and warfarin resistance. Orthologous to human CYP2C19 (cytochrome P450 family 2 subfamily C member 19) and CYP2C9 (cytochrome P450 family 2 subfamily C member 9); PARTICIPATES IN arachidonic acid metabolic pathway; linoleic acid metabolic pathway; retinol metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxytolbutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI265721; AI662255; CYPIIC40; cytochrome P450 2C40; cytochrome P450, 2c40
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1939,767,071 - 39,812,814 (-)EnsemblGRCm38mm10GRCm38
GRCm381939,767,073 - 39,812,814 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371939,841,563 - 39,887,304 (-)NCBIGRCm37mm9NCBIm37
MGSCv361939,820,384 - 39,866,039 (-)NCBImm8
Celera1940,549,902 - 40,595,384 (-)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cyp2c40
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558409
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.