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Gene: Trpm2 (transient receptor potential cation channel, subfamily M, member 2) Mus musculus
Symbol: Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Description: Exhibits ligand-gated calcium channel activity and manganese ion transmembrane transporter activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular response to temperature stimulus; and metal ion transport. Localizes to cytoplasmic vesicle membrane; integral component of plasma membrane; and lysosomal membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human TRPM2 (transient receptor potential cation channel subfamily M member 2); INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3',4,4',5-Pentachlorobiphenyl; ADP-D-ribose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9830168K16Rik; C79133; long transient receptor potential channel 2; LTrpC-2; LTRPC2; transient receptor potential cation channel subfamily M member 2; transient receptor potential channel 7; transient receptor protein 7; Trp7; TRPC7; Trrp7
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1077,907,722 - 77,970,563 (-)EnsemblGRCm38mm10GRCm38
GRCm381077,907,722 - 77,969,909 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371077,370,467 - 77,432,617 (-)NCBIGRCm37mm9NCBIm37
MGSCv361077,312,294 - 77,370,586 (-)NCBImm8
Celera1078,953,541 - 79,008,872 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Trpm2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558477
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.