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Gene: Tlr7 (toll-like receptor 7) Mus musculus
Symbol: Tlr7
Name: toll-like receptor 7
Description: Exhibits siRNA binding activity and single-stranded RNA binding activity. Involved in several processes, including defense response to virus; positive regulation of cytokine production; and toll-like receptor 7 signaling pathway. Localizes to the cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Used to study systemic lupus erythematosus. Is expressed in brain and liver. Orthologous to human TLR7 (toll like receptor 7); PARTICIPATES IN Toll-like receptor signaling pathway; influenza A pathway; measles pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Toll like receptor 7
Homo sapiens (human) : TLR7 (toll like receptor 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tlr7 (toll-like receptor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr7 (toll like receptor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR7 (toll like receptor 7)
Canis lupus familiaris (dog) : TLR7 (toll like receptor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr7 (toll like receptor 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38X167,303,380 - 167,330,574 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X163,742,863 - 163,768,460 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X162,649,036 - 162,674,633 (-)NCBImm8
CeleraX150,452,330 - 150,504,087 (-)NCBICelera
Cytogenetic MapX F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tlr7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558497
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.