Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tlr7 (toll-like receptor 7) Mus musculus
Analyze
Symbol: Tlr7
Name: toll-like receptor 7
Description: Exhibits siRNA binding activity and single-stranded RNA binding activity. Involved in several processes, including defense response to virus; positive regulation of cytokine production; and toll-like receptor 7 signaling pathway. Localizes to the cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Used to study systemic lupus erythematosus. Is expressed in brain and liver. Orthologous to human TLR7 (toll like receptor 7); PARTICIPATES IN Toll-like receptor signaling pathway; influenza A pathway; measles pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Toll like receptor 7
Orthologs:
Homo sapiens (human) : TLR7 (toll like receptor 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tlr7 (toll-like receptor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr7 (toll like receptor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR7 (toll like receptor 7)
Canis lupus familiaris (dog) : TLR7 (toll like receptor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr7 (toll like receptor 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38X167,303,380 - 167,330,574 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X163,742,863 - 163,768,460 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X162,649,036 - 162,674,633 (-)NCBImm8
CeleraX150,452,330 - 150,504,087 (-)NCBICelera
Cytogenetic MapX F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tlr7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558497
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.