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Gene: Kdm1a (lysine (K)-specific demethylase 1A) Mus musculus
Symbol: Kdm1a
Name: lysine (K)-specific demethylase 1A
Description: Exhibits several functions, including RNA polymerase II proximal promoter sequence-specific DNA binding activity; histone demethylase activity (H3-dimethyl-K4 specific); and transcription factor binding activity. Involved in several processes, including histone lysine demethylation; negative regulation of nitrogen compound metabolic process; and regulation of myeloid cell differentiation. Localizes to the nuclear chromatin. Is expressed in several structures, including brain; future pituitary; inner cell mass; reproductive system; and urinary system. Orthologous to human KDM1A (lysine demethylase 1A); PARTICIPATES IN histone modification pathway; Notch signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; Aof2; BRAF35-HDAC complex protein BHC110; D4Ertd478e; flavin-containing amine oxidase domain-containing protein 2; Kdm1; Lsd1; lysine (K)-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601
Homo sapiens (human) : KDM1A (lysine demethylase 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm1a (lysine demethylase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm1a (lysine demethylase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM1A (lysine demethylase 1A)
Canis lupus familiaris (dog) : KDM1A (lysine demethylase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm1a (lysine demethylase 1A)
Sus scrofa (pig) : KDM1A (lysine demethylase 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384136,550,533 - 136,602,787 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374136,106,448 - 136,158,638 (-)NCBIGRCm37mm9NCBIm37
MGSCv364135,822,633 - 135,874,786 (-)NCBImm8
Celera4134,744,880 - 134,796,951 (-)NCBICelera
Cytogenetic Map4 D3NCBI
cM Map468.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm1a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558503
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.