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Gene: Kdm1a (lysine (K)-specific demethylase 1A) Mus musculus
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Symbol: Kdm1a
Name: lysine (K)-specific demethylase 1A
Description: Exhibits several functions, including RNA polymerase II proximal promoter sequence-specific DNA binding activity; histone demethylase activity (H3-dimethyl-K4 specific); and transcription factor binding activity. Involved in several processes, including histone lysine demethylation; negative regulation of nitrogen compound metabolic process; and regulation of myeloid cell differentiation. Localizes to the nuclear chromatin. Is expressed in several structures, including brain; future pituitary; inner cell mass; reproductive system; and urinary system. Orthologous to human KDM1A (lysine demethylase 1A); PARTICIPATES IN histone modification pathway; Notch signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; Aof2; BRAF35-HDAC complex protein BHC110; D4Ertd478e; flavin-containing amine oxidase domain-containing protein 2; Kdm1; Lsd1; lysine (K)-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601
Orthologs:
Homo sapiens (human) : KDM1A (lysine demethylase 1A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm1a (lysine demethylase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm1a (lysine demethylase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM1A (lysine demethylase 1A)
Canis lupus familiaris (dog) : KDM1A (lysine demethylase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm1a (lysine demethylase 1A)
Sus scrofa (pig) : KDM1A (lysine demethylase 1A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384136,550,533 - 136,602,787 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374136,106,448 - 136,158,638 (-)NCBIGRCm37mm9NCBIm37
MGSCv364135,822,633 - 135,874,786 (-)NCBImm8
Celera4134,744,880 - 134,796,951 (-)NCBICelera
Cytogenetic Map4 D3NCBI
cM Map468.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm1a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558503
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.