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Gene: Megf10 (multiple EGF-like-domains 10) Mus musculus
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Symbol: Megf10
Name: multiple EGF-like-domains 10
CRRD ID: 1558549
Description: Exhibits Notch binding activity. Involved in several processes, including apoptotic cell clearance; myoblast migration; and skeletal muscle satellite cell proliferation. Localizes to phagocytic cup. Is expressed in brain; dorsal root ganglion; and retina layer. Human ortholog(s) of this gene implicated in early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ethanol; monosodium L-glutamate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3000002B06Rik; Gm331; multiple EGF-like domains protein 10; multiple epidermal growth factor-like domains protein 10
Orthologs:
Homo sapiens (human) : MEGF10 (multiple EGF like domains 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Megf10 (multiple EGF-like domains 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Megf10 (multiple EGF like domains 10)
Pan paniscus (bonobo/pygmy chimpanzee) : MEGF10 (multiple EGF like domains 10)
Canis lupus familiaris (dog) : MEGF10 (multiple EGF like domains 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Megf10 (multiple EGF like domains 10)
Sus scrofa (pig) : MEGF10 (multiple EGF like domains 10)
Chlorocebus sabaeus (African green monkey) : MEGF10 (multiple EGF like domains 10)
Heterocephalus glaber (naked mole-rat) : Megf10 (multiple EGF like domains 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391857,266,162 - 57,430,539 (+)NCBI
GRCm381857,133,090 - 57,297,467 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1857,133,090 - 57,297,467 (+)EnsemblGRCm38mm10GRCm38
MGSCv371857,292,744 - 57,457,121 (+)NCBIGRCm37mm9NCBIm37
MGSCv361857,258,844 - 57,422,835 (+)NCBImm8
Celera1858,443,454 - 58,608,465 (+)NCBICelera
Cytogenetic Map18D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Megf10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558549
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.