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Gene: Megf10 (multiple EGF-like-domains 10) Mus musculus
Symbol: Megf10
Name: multiple EGF-like-domains 10
CRRD ID: 1558549
Description: Exhibits Notch binding activity. Involved in several processes, including apoptotic cell clearance; myoblast migration; and skeletal muscle satellite cell proliferation. Localizes to phagocytic cup. Is expressed in brain; dorsal root ganglion; and retina layer. Human ortholog(s) of this gene implicated in early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ethanol; monosodium L-glutamate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3000002B06Rik; Gm331; multiple EGF-like domains protein 10; multiple epidermal growth factor-like domains protein 10
Homo sapiens (human) : MEGF10 (multiple EGF like domains 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Megf10 (multiple EGF-like domains 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Megf10 (multiple EGF like domains 10)
Pan paniscus (bonobo/pygmy chimpanzee) : MEGF10 (multiple EGF like domains 10)
Canis lupus familiaris (dog) : MEGF10 (multiple EGF like domains 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Megf10 (multiple EGF like domains 10)
Sus scrofa (pig) : MEGF10 (multiple EGF like domains 10)
Chlorocebus sabaeus (African green monkey) : MEGF10 (multiple EGF like domains 10)
Heterocephalus glaber (naked mole-rat) : Megf10 (multiple EGF like domains 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391857,266,162 - 57,430,539 (+)NCBI
GRCm381857,133,090 - 57,297,467 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1857,133,090 - 57,297,467 (+)EnsemblGRCm38mm10GRCm38
MGSCv371857,292,744 - 57,457,121 (+)NCBIGRCm37mm9NCBIm37
MGSCv361857,258,844 - 57,422,835 (+)NCBImm8
Celera1858,443,454 - 58,608,465 (+)NCBICelera
Cytogenetic Map18D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Megf10
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1558549
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.