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Gene: Mdc1 (mediator of DNA damage checkpoint 1) Rattus norvegicus
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Symbol: Mdc1
Name: mediator of DNA damage checkpoint 1
Description: Predicted to have FHA domain binding activity; identical protein binding activity; and protein C-terminus binding activity. Predicted to be involved in DNA repair. Predicted to localize to the chromosome; focal adhesion; and nuclear body. Orthologous to human MDC1 (mediator of DNA damage checkpoint 1); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0170; mediator of DNA damage checkpoint protein 1
Orthologs:
Homo sapiens (human) : MDC1 (mediator of DNA damage checkpoint 1)  HGNC  Alliance
Mus musculus (house mouse) : Mdc1 (mediator of DNA damage checkpoint 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdc1 (mediator of DNA damage checkpoint 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MDC1 (mediator of DNA damage checkpoint 1)
Canis lupus familiaris (dog) : MDC1 (mediator of DNA damage checkpoint 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdc1 (mediator of DNA damage checkpoint 1)
Sus scrofa (pig) : MDC1 (mediator of DNA damage checkpoint 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,405,017 - 3,419,831 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,404,711 - 3,419,831 (-)Ensembl
Rnor_5.0205,502,120 - 5,516,934 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,042,953 - 3,057,607 (-)NCBIRGSC3.4rn4RGSC3.4
Celera20321,426 - 336,070 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mdc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1559468
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.