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Gene: Sco1 (synthesis of cytochrome C oxidase 1) Rattus norvegicus
Symbol: Sco1
Name: synthesis of cytochrome C oxidase 1
CRRD ID: 1559538
Description: Predicted to be involved in cellular copper ion homeostasis; mitochondrial cytochrome c oxidase assembly; and negative regulation of proteasomal protein catabolic process. Predicted to localize to host cell mitochondrial intermembrane space; integral component of mitochondrial inner membrane; and myofibril. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human SCO1 (synthesis of cytochrome C oxidase 1); INTERACTS WITH bisphenol A; finasteride; flutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC497930; RGD1559538; SCO cytochrome c oxidase assembly protein 1; SCO cytochrome oxidase deficient homolog 1; SCO cytochrome oxidase deficient homolog 1 (yeast); SCO1 cytochrome c oxidase assembly protein; similar to SCO cytochrome oxidase deficient homolog 1 (yeast)
Homo sapiens (human) : SCO1 (synthesis of cytochrome C oxidase 1)  HGNC  Alliance
Mus musculus (house mouse) : Sco1 (SCO1 cytochrome c oxidase assembly protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102030058 (protein SCO1 homolog, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100988585 (transmembrane protein 220)
Canis lupus familiaris (dog) : SCO1 (synthesis of cytochrome C oxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101974307 (protein SCO1 homolog, mitochondrial)
Sus scrofa (pig) : SCO1 (synthesis of cytochrome C oxidase 1)
Chlorocebus sabaeus (African green monkey) : SCO1 (SCO1, cytochrome c oxidase assembly protein)
Heterocephalus glaber (naked mole-rat) : LOC101701770 (protein SCO1 homolog, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01053,595,854 - 53,608,437 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,595,854 - 53,608,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,346,887 - 53,359,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,751,335 - 53,763,923 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1050,927,764 - 50,940,347 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sco1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1559538
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.