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Gene: Sco1 (synthesis of cytochrome C oxidase 1) Rattus norvegicus
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Symbol: Sco1
Name: synthesis of cytochrome C oxidase 1
CRRD ID: 1559538
Description: Predicted to be involved in cellular copper ion homeostasis; mitochondrial cytochrome c oxidase assembly; and negative regulation of proteasomal protein catabolic process. Predicted to localize to host cell mitochondrial intermembrane space; integral component of mitochondrial inner membrane; and myofibril. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human SCO1 (synthesis of cytochrome C oxidase 1); INTERACTS WITH bisphenol A; finasteride; flutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC497930; RGD1559538; SCO cytochrome c oxidase assembly protein 1; SCO cytochrome oxidase deficient homolog 1; SCO cytochrome oxidase deficient homolog 1 (yeast); SCO1 cytochrome c oxidase assembly protein; similar to SCO cytochrome oxidase deficient homolog 1 (yeast)
Orthologs:
Homo sapiens (human) : SCO1 (synthesis of cytochrome C oxidase 1)  HGNC  Alliance
Mus musculus (house mouse) : Sco1 (SCO1 cytochrome c oxidase assembly protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102030058 (protein SCO1 homolog, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100988585 (transmembrane protein 220)
Canis lupus familiaris (dog) : SCO1 (synthesis of cytochrome C oxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101974307 (protein SCO1 homolog, mitochondrial)
Sus scrofa (pig) : SCO1 (synthesis of cytochrome C oxidase 1)
Chlorocebus sabaeus (African green monkey) : SCO1 (SCO1, cytochrome c oxidase assembly protein)
Heterocephalus glaber (naked mole-rat) : LOC101701770 (protein SCO1 homolog, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01053,595,854 - 53,608,437 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,595,854 - 53,608,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,346,887 - 53,359,470 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,751,335 - 53,763,923 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1050,927,764 - 50,940,347 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sco1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1559538
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.