Gene: Med1 (mediator complex subunit 1) Rattus norvegicus
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Symbol: Med1
Name: mediator complex subunit 1
Description: Exhibits nuclear hormone receptor binding activity, nucleic acid binding activity, and transcription coregulator activity; contributes to ubiquitin protein ligase activity; involved in several processes, including brain development, cellular response to thyroid hormone stimulus, and positive regulation of transcription by RNA polymerase II; localizes to the intracellular organelle, protein-DNA complex, and ubiquitin ligase complex; orthologous to human MED1 (mediator complex subunit 1); PARTICIPATES IN cortisol signaling pathway; estrogen signaling pathway; RNA polymerase II transcription pathway; INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC497991; mediator of RNA polymerase II transcription subunit 1; RGD1559552; similar to peroxisome proliferator-activated receptor binding protein
Orthologs:
Homo sapiens (human) : MED1 (mediator complex subunit 1)  HGNC  Alliance
Mus musculus (house mouse) : Med1 (mediator complex subunit 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Med1 (mediator complex subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MED1 (mediator complex subunit 1)
Canis lupus familiaris (dog) : MED1 (mediator complex subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Med1 (mediator complex subunit 1)
Sus scrofa (pig) : MED1 (mediator complex subunit 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,101,560 - 86,145,271 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01085,899,172 - 85,942,182 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41086,917,525 - 86,959,080 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1081,896,663 - 81,937,929 (-)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Med1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1559552
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.