Gene: Srf (serum response factor) Rattus norvegicus
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Symbol: Srf
Name: serum response factor
Description: Exhibits histone deacetylase binding activity and sequence-specific DNA binding activity; involved in several processes, including cellular response to glucose stimulus, long-term memory, and negative regulation of cell migration; localizes to the nucleus; used to study hepatocellular carcinoma and hypertension; orthologous to human SRF (serum response factor); PARTICIPATES IN platelet-derived growth factor signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC501099; RGD1559787; serum response factor (c-fos serum response element-binding transcription factor); similar to serum response factor
Orthologs:
Homo sapiens (human) : SRF (serum response factor)  HGNC  Alliance
Mus musculus (house mouse) : Srf (serum response factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srf (serum response factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SRF (serum response factor)
Canis lupus familiaris (dog) : SRF (serum response factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srf (serum response factor)
Sus scrofa (pig) : SRF (serum response factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0916,737,637 - 16,747,226 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0915,642,584 - 15,652,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,788,378 - 9,797,639 (+)NCBIRGSC3.4rn4RGSC3.4
Celera912,173,971 - 12,183,234 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Srf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1559787
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.