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Gene: Gen1 (GEN1 Holliday junction 5' flap endonuclease) Rattus norvegicus
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Symbol: Gen1
Name: GEN1 Holliday junction 5' flap endonuclease
Description: Predicted to have several functions, including deoxyribonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA metabolic process and regulation of cell cycle process. Predicted to localize to the centrosome. Orthologous to human GEN1 (GEN1 Holliday junction 5' flap endonuclease); INTERACTS WITH 1,2-dimethylhydrazine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: flap endonuclease GEN homolog 1; Gen endonuclease homolog 1; Gen endonuclease homolog 1 (Drosophila); Gen homolog 1, endonuclease; Gen homolog 1, endonuclease (Drosophila); LOC298884; RGD1559792; similar to RIKEN cDNA 5830483C08 gene
Orthologs:
Homo sapiens (human) : GEN1 (GEN1 Holliday junction 5' flap endonuclease)  HGNC  Alliance
Mus musculus (house mouse) : Gen1 (GEN1, Holliday junction 5' flap endonuclease)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gen1 (GEN1 Holliday junction 5' flap endonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : GEN1 (GEN1 Holliday junction 5' flap endonuclease)
Canis lupus familiaris (dog) : GEN1 (GEN1 Holliday junction 5' flap endonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gen1 (GEN1 Holliday junction 5' flap endonuclease)
Sus scrofa (pig) : GEN1 (GEN1 Holliday junction 5' flap endonuclease)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0636,910,064 - 36,940,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0646,660,177 - 46,690,981 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4634,679,618 - 34,709,812 (-)NCBIRGSC3.4rn4RGSC3.4
Celera633,348,660 - 33,378,853 (-)NCBICelera
Cytogenetic Map6q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gen1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1559792
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.