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Gene: Grem2 (gremlin 2, DAN family BMP antagonist) Rattus norvegicus
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Symbol: Grem2
Name: gremlin 2, DAN family BMP antagonist
Description: Predicted to have BMP binding activity; heparin binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: gremlin 2; gremlin 2 homolog, cysteine knot superfamily; gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis) ; gremlin 2, cysteine knot superfamily, homolog; gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis); gremlin-2; LOC289264; RGD1560008; similar to PRDC
Orthologs:
Homo sapiens (human) : GREM2 (gremlin 2, DAN family BMP antagonist)  HGNC  Alliance
Mus musculus (house mouse) : Grem2 (gremlin 2, DAN family BMP antagonist)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grem2 (gremlin 2, DAN family BMP antagonist)
Pan paniscus (bonobo/pygmy chimpanzee) : GREM2 (gremlin 2, DAN family BMP antagonist)
Canis lupus familiaris (dog) : GREM2 (gremlin 2, DAN family BMP antagonist)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grem2 (gremlin 2, DAN family BMP antagonist)
Sus scrofa (pig) : GREM2 (gremlin 2, DAN family BMP antagonist)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01392,894,431 - 92,988,137 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01397,359,449 - 97,453,188 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41390,528,920 - 90,622,303 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1386,379,414 - 86,472,331 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Grem2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560008
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.