Gene: Map2k7 (mitogen activated protein kinase kinase 7) Rattus norvegicus
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Symbol: Map2k7
Name: mitogen activated protein kinase kinase 7
Description: Exhibits several functions, including ATP binding activity, JUN kinase kinase activity, and magnesium ion binding activity; involved in several processes, including activation of JUN kinase activity, cellular response to sorbitol, and positive regulation of neuron apoptotic process; localizes to the cytosol and nucleus; orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; adenosine signaling pathway; FasL mediated signaling pathway; INTERACTS WITH bisphenol A; cadmium dichloride; nickel sulfate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2; c-Jun N-terminal kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 7; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAPK/ERK kinase 7; MAPKK 7; Mapkk7; MEK 7; Mek7; Mkk7
Orthologs:
Homo sapiens (human) : MAP2K7 (mitogen-activated protein kinase kinase 7)  HGNC  Alliance
Mus musculus (house mouse) : Map2k7 (mitogen-activated protein kinase kinase 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Map2k7 (mitogen-activated protein kinase kinase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Canis lupus familiaris (dog) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Map2k7 (mitogen-activated protein kinase kinase 7)
Sus scrofa (pig) : MAP2K7 (mitogen-activated protein kinase kinase 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0122,546,278 - 2,555,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0124,698,912 - 4,708,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,545,407 - 1,552,353 (-)NCBIRGSC3.4rn4RGSC3.4
Celera124,407,043 - 4,413,990 (+)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Map2k7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560043
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.