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Gene: Map2k7 (mitogen activated protein kinase kinase 7) Rattus norvegicus
Symbol: Map2k7
Name: mitogen activated protein kinase kinase 7
Description: Exhibits several functions, including ATP binding activity; JUN kinase kinase activity; and magnesium ion binding activity. Involved in several processes, including activation of JUN kinase activity; cellular response to sorbitol; and positive regulation of neuron apoptotic process. Localizes to cytosol and nucleus. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; adenosine signaling pathway; FasL mediated signaling pathway; INTERACTS WITH bisphenol A; cadmium dichloride; N-methyl-4-phenylpyridinium.
Type: protein-coding
Also known as: 2; c-Jun N-terminal kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 7; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAPK/ERK kinase 7; MAPKK 7; Mapkk7; MEK 7; Mek7; Mkk7
Homo sapiens (human) : MAP2K7 (mitogen-activated protein kinase kinase 7)  HGNC  Alliance
Mus musculus (house mouse) : Map2k7 (mitogen-activated protein kinase kinase 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Map2k7 (mitogen-activated protein kinase kinase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Canis lupus familiaris (dog) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Map2k7 (mitogen-activated protein kinase kinase 7)
Sus scrofa (pig) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Chlorocebus sabaeus (African green monkey) : MAP2K7 (mitogen-activated protein kinase kinase 7)
Heterocephalus glaber (naked mole-rat) : Map2k7 (mitogen-activated protein kinase kinase 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0122,546,278 - 2,555,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,548,218 - 2,555,164 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,698,912 - 4,708,078 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,545,407 - 1,552,353 (-)NCBIRGSC3.4rn4RGSC3.4
Celera124,407,043 - 4,413,990 (+)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Map2k7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560043
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.