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Gene: Dusp3 (dual specificity phosphatase 3) Rattus norvegicus
Symbol: Dusp3
Name: dual specificity phosphatase 3
Description: Predicted to have cytoskeletal protein binding activity; phosphoprotein phosphatase activity; and receptor tyrosine kinase binding activity. Involved in in utero embryonic development. Predicted to localize to cytosol; immunological synapse; and nucleoplasm. Orthologous to human DUSP3 (dual specificity phosphatase 3); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; acrylamide; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related); dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)-like; dual specificity protein phosphatase 3; LOC100365414; LOC498003; MGC189429; RGD1560049; similar to Dual specificity protein phosphatase 3 (T-DSP11); vaccinia virus phosphatase VH1-related
Homo sapiens (human) : DUSP3 (dual specificity phosphatase 3)  HGNC  Alliance
Mus musculus (house mouse) : Dusp3 (dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp3 (dual specificity phosphatase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP3 (dual specificity phosphatase 3)
Canis lupus familiaris (dog) : DUSP3 (dual specificity phosphatase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp3 (dual specificity phosphatase 3)
Sus scrofa (pig) : DUSP3 (dual specificity phosphatase 3)
Chlorocebus sabaeus (African green monkey) : DUSP3 (dual specificity phosphatase 3)
Heterocephalus glaber (naked mole-rat) : Dusp3 (dual specificity phosphatase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01089,904,578 - 89,918,296 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,904,560 - 89,918,427 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,697,004 - 89,710,720 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,031,206 - 91,044,858 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1085,639,184 - 85,651,010 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dusp3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560049
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.