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Gene: Tdp2 (tyrosyl-DNA phosphodiesterase 2) Rattus norvegicus
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Symbol: Tdp2
Name: tyrosyl-DNA phosphodiesterase 2
Description: Predicted to have metal ion binding activity; phosphoric diester hydrolase activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair and neuron development. Predicted to localize to PML body; aggresome; and cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Orthologous to human TDP2 (tyrosyl-DNA phosphodiesterase 2); INTERACTS WITH bisphenol A; resveratrol; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5'-Tyr-DNA phosphodiesterase; 5'-tyrosyl-DNA phosphodiesterase; LOC498749; MGC124734; similar to putative TRAF and TNF receptor associated protein; Traf and Tnf receptor associated protein; TRAF and TNF receptor-associated protein; Ttrap; tyr-DNA phosphodiesterase 2
Orthologs:
Homo sapiens (human) : TDP2 (tyrosyl-DNA phosphodiesterase 2)  HGNC  Alliance
Mus musculus (house mouse) : Tdp2 (tyrosyl-DNA phosphodiesterase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdp2 (tyrosyl-DNA phosphodiesterase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TDP2 (tyrosyl-DNA phosphodiesterase 2)
Canis lupus familiaris (dog) : TDP2 (tyrosyl-DNA phosphodiesterase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdp2 (tyrosyl-DNA phosphodiesterase 2)
Sus scrofa (pig) : TDP2 (tyrosyl-DNA phosphodiesterase 2)
Chlorocebus sabaeus (African green monkey) : TDP2 (tyrosyl-DNA phosphodiesterase 2)
Heterocephalus glaber (naked mole-rat) : Tdp2 (tyrosyl-DNA phosphodiesterase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01742,229,667 - 42,241,025 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,229,642 - 42,241,066 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,097,466 - 44,108,824 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,290,530 - 47,301,849 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1739,866,248 - 39,877,568 (-)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tdp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560342
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.