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Gene: Gmppb (GDP-mannose pyrophosphorylase B) Rattus norvegicus
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Symbol: Gmppb
Name: GDP-mannose pyrophosphorylase B
Description: Predicted to have mannose-1-phosphate guanylyltransferase activity. Predicted to be involved in GDP-mannose biosynthetic process. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in Walker-Warburg syndrome; autosomal recessive limb-girdle muscular dystrophy type 2T; and muscular dystrophy-dystroglycanopathy. Orthologous to human GMPPB (GDP-mannose pyrophosphorylase B); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,4,6-trinitrotoluene; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC363145; mannose-1-phosphate guanyltransferase beta; RGD1560458; similar to GDP-mannose pyrophosphorylase B
Orthologs:
Homo sapiens (human) : GMPPB (GDP-mannose pyrophosphorylase B)  HGNC  Alliance
Mus musculus (house mouse) : Gmppb (GDP-mannose pyrophosphorylase B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gmppb (GDP-mannose pyrophosphorylase B)
Pan paniscus (bonobo/pygmy chimpanzee) : GMPPB (GDP-mannose pyrophosphorylase B)
Canis lupus familiaris (dog) : GMPPB (GDP-mannose pyrophosphorylase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gmppb (GDP-mannose pyrophosphorylase B)
Sus scrofa (pig) : GMPPB (GDP-mannose pyrophosphorylase B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08116,826,251 - 116,856,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,180,562 - 116,210,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,317,165 - 113,346,646 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8108,042,518 - 108,071,499 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gmppb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560458
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.