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Gene: Fzd8 (frizzled class receptor 8) Rattus norvegicus
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Symbol: Fzd8
Name: frizzled class receptor 8
Description: Predicted to have several functions, including PDZ domain binding activity; Wnt-activated receptor activity; and Wnt-protein binding activity. Predicted to be involved in several processes, including T cell differentiation in thymus; Wnt signaling pathway; and positive regulation of JUN kinase activity. Predicted to localize to Wnt-Frizzled-LRP5/6 complex and integral component of membrane. Orthologous to human FZD8 (frizzled class receptor 8); PARTICIPATES IN Wnt signaling pathway; basal cell carcinoma pathway; Wnt signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: frizzled family receptor 8; frizzled homolog 8; frizzled homolog 8 (Drosophila); frizzled-8; fz-8; MGC112790; similar to transmembrane receptor
Orthologs:
Homo sapiens (human) : FZD8 (frizzled class receptor 8)  HGNC  Alliance
Mus musculus (house mouse) : Fzd8 (frizzled class receptor 8)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FZD8 (frizzled class receptor 8)
Sus scrofa (pig) : FZD8 (frizzled class receptor 8)
Chlorocebus sabaeus (African green monkey) : FZD8 (frizzled class receptor 8)
Heterocephalus glaber (naked mole-rat) : Fzd8 (frizzled class receptor 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01762,259,910 - 62,267,239 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1762,262,129 - 62,265,113 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01764,033,702 - 64,040,990 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41765,968,739 - 65,971,724 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1758,595,549 - 58,598,534 (+)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Fzd8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560525
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.