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Gene: Pxdn (peroxidasin) Rattus norvegicus
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Symbol: Pxdn
Name: peroxidasin
Description: Predicted to have extracellular matrix structural constituent; heme binding activity; and peroxidase activity. Predicted to be involved in extracellular matrix organization; hydrogen peroxide catabolic process; and oxidation-reduction process. Predicted to localize to the collagen-containing extracellular matrix; endoplasmic reticulum; and extracellular space. Human ortholog(s) of this gene implicated in anterior segment mesenchymal dysgenesis. Orthologous to human PXDN (peroxidasin); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC314016; melanoma-associated antigen MG50; PE responsive protein c64; Perc64; peroxidasin homolog; peroxidasin homolog (Drosophila); similar to mKIAA0230 protein; Vpo1
Orthologs:
Homo sapiens (human) : PXDN (peroxidasin)  HGNC  Alliance
Mus musculus (house mouse) : Pxdn (peroxidasin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pxdn (peroxidasin)
Pan paniscus (bonobo/pygmy chimpanzee) : PXDN (peroxidasin)
Canis lupus familiaris (dog) : PXDN (peroxidasin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pxdn (peroxidasin)
Sus scrofa (pig) : PXDN (peroxidasin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0648,866,496 - 48,982,368 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0657,551,559 - 57,663,427 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4647,878,710 - 47,914,112 (+)NCBIRGSC3.4rn4RGSC3.4
Celera645,788,867 - 45,866,653 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pxdn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560694
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.