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Gene: Hook3 (hook microtubule-tethering protein 3) Rattus norvegicus
Symbol: Hook3
Name: hook microtubule-tethering protein 3
Description: Predicted to have several functions, including cytoskeletal protein binding activity; dynein intermediate chain binding activity; and dynein light chain binding activity. Predicted to be involved in several processes, including early endosome to late endosome transport; microtubule cytoskeleton organization; and nervous system development. Predicted to colocalize with HOPS complex. Orthologous to human HOOK3 (hook microtubule tethering protein 3); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: hook homolog 3; hook homolog 3 (Drosophila)
Homo sapiens (human) : HOOK3 (hook microtubule tethering protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Hook3 (hook microtubule tethering protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hook3 (hook microtubule tethering protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HOOK3 (hook microtubule tethering protein 3)
Canis lupus familiaris (dog) : HOOK3 (hook microtubule tethering protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hook3 (hook microtubule tethering protein 3)
Sus scrofa (pig) : HOOK3 (hook microtubule tethering protein 3)
Chlorocebus sabaeus (African green monkey) : HOOK3 (hook microtubule tethering protein 3)
Heterocephalus glaber (naked mole-rat) : Hook3 (hook microtubule tethering protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01670,710,347 - 70,818,789 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01670,376,538 - 70,483,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,338,144 - 70,424,173 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1663,865,670 - 63,960,092 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Hook3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1560960
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.