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Gene: Map3k20 (mitogen-activated protein kinase kinase kinase 20) Rattus norvegicus
Symbol: Map3k20
Name: mitogen-activated protein kinase kinase kinase 20
Description: Predicted to have ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including cellular response to gamma radiation; cytoskeleton organization; and negative regulation of cell cycle. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in centronuclear myopathy. Orthologous to human MAP3K20 (mitogen-activated protein kinase kinase kinase 20); PARTICIPATES IN p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-catechin (ortholog); (-)-anisomycin (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC311743; mitogen-activated protein kinase kinase kinase MLT; MLTK; RGD1561394; similar to MLTK-beta; sterile alpha motif and leucine zipper containing kinase AZK; Zak
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0358,965,025 - 59,120,507 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0365,435,276 - 65,598,052 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4354,767,724 - 54,915,022 (+)NCBIRGSC3.4rn4RGSC3.4
Celera356,670,166 - 56,831,147 (+)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Map3k20
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561394
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.