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Gene: E2f3 (E2F transcription factor 3) Rattus norvegicus
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Symbol: E2f3
Name: E2F transcription factor 3
Description: Predicted to contribute to DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including negative regulation of fat cell proliferation; positive regulation of vascular associated smooth muscle cell apoptotic process; and regulation of transcription by RNA polymerase II. Predicted to localize to the RNA polymerase II transcription factor complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human E2F3 (E2F transcription factor 3); PARTICIPATES IN cell cycle pathway, mitotic; ceramide signaling pathway; chronic myeloid leukemia pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E2F transcription factor 3-like; LOC100361421; LOC291105; RGD1561600; similar to E2f3 protein; similar to Transcription factor E2F3 (E2F-3); transcription factor E2F3
Orthologs:
Homo sapiens (human) : E2F3 (E2F transcription factor 3)  HGNC  Alliance
Mus musculus (house mouse) : E2f3 (E2F transcription factor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f3 (E2F transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F3 (E2F transcription factor 3)
Canis lupus familiaris (dog) : E2F3 (E2F transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f3 (E2F transcription factor 3)
Sus scrofa (pig) : E2F3 (E2F transcription factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01736,334,136 - 36,408,831 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01737,641,855 - 37,716,592 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41741,079,346 - 41,145,568 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1734,130,042 - 34,203,210 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on E2f3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561600
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.