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Gene: Thoc2 (THO complex 2) Rattus norvegicus
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Symbol: Thoc2
Name: THO complex 2
Description: Predicted to have mRNA binding activity. Involved in negative regulation of neuron projection development. Predicted to colocalize with the nuclear chromosome, telomeric region. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human THOC2 (THO complex 2); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; spliceosome pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; chloroprene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC313308; RGD1561623; similar to THO complex 2; THO complex subunit 2
Orthologs:
Homo sapiens (human) : THOC2 (THO complex 2)  HGNC  Alliance
Mus musculus (house mouse) : Thoc2 (THO complex 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thoc2 (THO complex 2)
Pan paniscus (bonobo/pygmy chimpanzee) : THOC2 (THO complex 2)
Canis lupus familiaris (dog) : THOC2 (THO complex 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thoc2 (THO complex 2)
Sus scrofa (pig) : THOC2 (THO complex 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X128,153,824 - 128,268,327 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X128,246,548 - 128,361,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X3,196,205 - 3,310,749 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX119,751,149 - 119,864,843 (-)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Thoc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1561623
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.